The OrganoTEER® device is a high-throughput solution for measuring Trans-Endothelial and Epithelial Electrical Resistance (TEER) in 3D tissue models. Built for use with the OrganoPlate® platform, it provides non-disruptive, real-time assessment of barrier integrity across epithelial and endothelial tissues—without artificial membranes.This flyer outlines how OrganoTEER enables accurate, membrane-free TEER readouts across a range of applications, from blood-brain barrier models to gut and vascular toxicity screening.What’s Inside:Overview of the OrganoTEER® device and softwareTEER measurement in 3D perfused models under flowBarrier measured in under 2 minutesIntegration with time-lapse studies in incubatorsCompatibility with OrganoReady® pre-validated tissue modelsApplications Highlighted in the Flyer:Blood-Brain Barrier Toxicity – Track dose-dependent barrier disruptionVascular Toxicity – Assess endothelial function under inflammatory stressGastrointestinal Toxicity – Measure compound-induced barrier loss in colon organoidsCytotoxicity & Cell Viability – Combine TEER with LDH and ATP assays for comprehensive analysisWith the OrganoTEER® system, researchers can easily quantify subtle changes in barrier function in a physiologically relevant setting—supporting improved predictive toxicology and mechanistic insights.