3D Human CNS Models
MIMETAS’ CNS models comprise iPSC-derived neurons, establishing directional axonal outgrowth and segregation.
The system enables research into axonal biology, neuropathies, and CIPN, with predictive responses to neurotoxic agents for drug testing and mechanistic studies.
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Neuronal Complexity Tailored to Your Research Question
MIMETAS’ neurite outgrowth model separates axons from neuronal somas in a compartmentalized, perfused architecture that supports precise neurite tracking and unobstructed axonal growth.
Available Model Configurations:
3D neuronal monocultures (Motor or sensory neurons embedded in ECM)
Glia-enhanced cultures (Astrocytes, Schwann cells, or other supporting glia)
Patient-derived or iPSC-based neurons (Customizable for donor-specific modeling)
Compartmentalized architecture (Axon–soma separation with PhaseGuides™ for neurite tracking)
Perfused architecture with unobstructed growth
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A Range of Applications
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Axonal toxicity profiling
Chemotherapy-induced peripheral neuropathy (CIPN) modeling
Neurite regeneration & outgrowth studies
Screening of ADCs and microtubule inhibitors
