MIMETAS partner in €4.5mn EU Interreg project BIOMAT
Engineering 3D microenvironments of vascularised bone and muscle
The objective of the 'Biomat' project is to develop a platform for high-throughput testing of biomaterials in a physiologically relevant environment on-a-chip. The innovative aspects of this platform are a 3D environment that mimics relevant tissues in which novel and existing biomaterials can be integrated for reliable in vitro testing and monitoring.
Bones- and Muscles-on-a-Chip
Within this project, 3D microenvironments of vascularised bone and muscle will be engineered on microfluidic chips, and used to test the performance of biomaterials, such as hip implants, bone fillers and stents. MIMETAS OrganoPlate® technology offers unique functionalities, not possible with conventional 2D or 3D culture, allowing to better replicate the complex microenvironment of bones and muscles. In addition, MIMETAS's perfused vascular beds, that recapitulate hallmark features of human microvessels, will play an important role in the project.
Partners and Funding
Other partners in the project are: Universiteit Maastricht - MERLN Institute for Technology-Inspired Regenerative Medicine (NL), Katholieke Universiteit Leuven (BE), Xplore Instruments B.V. (NL), Leids Universitair Medisch Centrum (NL), Tenco DDM (BE), DSM R&D Solutions B.V. (NL) and Interuniversitair Micro-Elektronica Centrum - IMEC (BE).
The project was awarded an Interreg Flanders-The Netherlands grant, support from the Dutch Department of Economic Affairs and the Province of Zuid-Holland on a total project budget of €4.5mn.