How do you assess compound-induced Caco-2 toxicity?
Take your gut research to the next level with our 40 or 64 ready-to-use Caco-2 tubules to assess gut permeability, compound toxicity, and transport.
Do you want to perform your toxicology experiments in human-relevant, 3D tissue models but don’t have the time or experience to build your own? And why spend 21 days to culture Caco-2 in Transwells when you could get started with your assay right away?
A crucial part of developing novel and successful therapies for unsolved diseases entails the identification of adverse drug-induced effects in the preclinical phase of drug development to avert organ injuries and further complications at later stages. Permeability is a pivotal factor in contributing to such drug-induced effects, influencing the drug’s toxicological effects to the intestinal barrier and overall efficacy by absorption, distribution, metabolism and excretion (ADME) properties.
Get started with our OrganoReady® Colon Caco-2 today, featuring ready-to-use perfused Caco-2 tubules to assess permeability, absorption, transport, compound toxicity and barrier integrity (TEER) without any culturing time.
