OrganoPlate® Caco-2 | Mimetas

OrganoPlate® Caco-2

OrganoPlate® Caco-2

OrganoPlate® Caco-2

The OrganoPlate® Caco-2 is an OrganoPlate 3-lane featuring ready-to-use Caco-2 tubules. The Caco-2 cell epithelial barrier tubules allow for apical and basal access enabling barrier integrity and transport assays. The gut model lends itself to study toxicity, transport and disease or can be used for fundamental research on the intestinal barrier.

Product specifications

  • OrganoPlate® 3-lane
  • 38x Caco-2 Tubules + 2x no cell control
  • Caco-2 cell line: Human Caucasian colon adenocarcinoma, Wild-Type. 
  • ECM: Collagen I (Rat Tail)

Benefits

Caco-2 tubules
  • Provides leak tight and confluent tubule, reducing maintenance and handling time
  • Full functionality after transport
  • Cultures are usable for 7 days after arrival
  • High quality assurance
  • Compatible with automated procedures
  • Easy-to-use

Suggested applications

  • Drug-induced toxicity
  • Intestinal Permeability
  • Drug to drug studies with P-gp transporter

Four steps to get started with the OrganoPlate Caco-2

Four steps to get started with the Assay Ready OrganoPlate®

What else do I need?

  • OrganoFlow® L/S (MIMETAS)
  • Pipetting reservoirs 50 ml (e.g. VWR no. 613-1183)
  • Multichannel pipette 5-350 µL (e.g. Sartorius® no. 730361)
  • Multichannel tips (e.g. Sartorius® 790351)
  • Eppendorf® Repeater® M4 Dispenser (Eppendorf® no. 4982000322)
  • Eppendorf® Combitips advanced® pipette tips Biopur® grade, 0.1 ml     
  • Sartorius® eLINE® Electronic Pipette for volumes between 0.2-10 µL (Sartorius® no. 730021)
  • Sartorius® 0.1-10 µL tips (Sartorius® no. 790010)
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