• We offer tailored partnerships to support and transform drug discovery.

    Every collaboration is a bespoke arrangement, meticulously designed to discover new compounds and targets in patient relevant disease models.

  • MIMETAS offers flexible fee-for-service solutions for therapy prioritization, optimization, and de-risking of compounds.

    As an extension of your team, MIMETAS provides the expertise and resources needed for effective research and development.

  • Our OrganoReady program is made for you when you need optimized assays for investigational toxicology.

    We guarantee OrganoReady performance according to specifications, in a fast and convenient sales transaction with a clear fee structure.

  • Giving you some food for thought. Read our blogs to learn more about 3D tissue culture, research backgrounds, developments, and its future outlook.

  • Get inspired by research done by our scientists, partners, and customers around the globe.

  • Learn about our mission, vision, the history of the company, and find out what we mean with MIMETAS-do.
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Applications

Complex tissues, in a relevant in vitro microenvironment
Capture stunning biology in the most versatile and user-friendly 3D tissue culture platform ever. The OrganoPlate® enables you to study relevant 3D tissue biology by incorporating perfused tubules, co-culture, and full control over the tissue microenvironment.


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Perfused Tubules
  • Polarized tubular tissues against an extracellular matrix (ECM)​
  • Easy apical and basolateral access
  • Perfusion of the tubules mimicking shear stress
  • No artificial membranes
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Cell-Cell Interactions
  • Co-culture different cell types without artificial membranes​​
  • Enable stratified co-cultures with relevant tissue structures​​
  • Study cellular interactions, cell-cell signaling, migration

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Angiogenesis
  • Perfused 3D microvasculature​​
  • Stable capillary structure for 4+ days​​
  • Tip-stalk cell hierarchy & anastomosis​​
  • Investigate microvascular damage, tumor angiogenesis, fibrosis​​
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Vascularization
  • In vitro grafting of target tissues on a vascular bed​​
  • ​Study interaction between perfused vasculature & target tissues​​
  • ​Spheroids, organoids, tissue fragments ​​
  • Patient-derived tissue grafting in vitro: an alternative to PDX mice
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3D Cell Migration
  • Study immune, tumor, fibroblast and mesenchymal stem cell migration through an extracellular matrix
  • No obstruction by artificial membranes
  • Allows excellent imaging, cell tracing & quantification
  • Stable chemotactic gradients over time
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