Do I need an OrganoFlow®?
Except for neuronal cultures, all our tissue culture models (i.e. liver, gut, kidney, vasculature, cancer, etc.) were shown to benefit strongly from medium perfusion. Perfused cultures show improved cell viability, the polarization of tubular structures, and upregulation of relevant transporters.
If you first want to try the OrganoPlate before purchasing a rocker, you can use a regular interval rocker for your first experiments. We’ve observed the formation of tubular structures of HUVECs using a regular interval rocker. However, to obtain optimal barrier formation and allow more controlled flow profiles, the OrganoFlow® is advised.