In this poster, we present a Chemotherapy-Induced Peripheral Neuropathy on-a-chip. This model was developed to mimic chemotherapy-induced peripheral neuropathy (CIPN) in human iPSC-derived motor neurons, offering a scalable and automation-compatible solution for assessing the neurotoxicity of chemotherapeutic drugs. By demonstrating dose-dependent and time-sensitive damage to neuronal networks, our model stands as a critical tool in the development of safer chemotherapy treatments, facilitating enhanced patient care and recovery pathways.
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